pmx_nlmixr

Creates pmx controller from an nlimxr fit object

At Novartis, we aimed at standardizing the set of diagnostic plots used for modeling
activities in order to reduce the overall effort required for generating such plots.
For this, we developed a guidance that proposes an adequate set of diagnostics and a toolbox,
called 'ggPMX' to execute them. 'ggPMX' is a toolbox that can generate all diagnostic plots at a quality sufficient
for publication and submissions using few lines of code. This package focuses on plots recommended by ISoP
<doi:10.1002/psp4.12161>. While not required, you can get/install the 'R' 'lixoftConnectors'
package in the 'Monolix' installation, as described at the following url
<https://monolix.lixoft.com/monolix-api/lixoftconnectors_installation/>.
When 'lixoftConnectors' is available, 'R' can use 'Monolix' directly to create the required
Chart Data instead of exporting it from the 'Monolix' gui.

Matthew Fidler

ggPMX

'ggplot2' Based Tool to Facilitate Diagnostic Plots for NLME
Models

pmx_nlmixr function

<dl><dt>fit</dt>
<dd>nlmixr object</dd>
<dt>dvid</dt>
<dd>[Optional] <code>character</code> observation type parameter.</dd>
<dt>conts</dt>
<dd>[Optional]<code>character</code> vector of continuous covariates</dd>
<dt>cats</dt>
<dd>[Optional]<code>character</code> vector of categorical covariates</dd>
<dt>strats</dt>
<dd>[Optional]<code>character</code> extra stratification variables</dd>
<dt>endpoint</dt>
<dd><code>pmxEndpointClass</code> or <code>integer</code> or <code>charcater</code> defalut to NULL
of the endpoint code. <code>pmx_endpoint</code></dd>
<dt>settings</dt>
<dd>[Optional]<code>pmxSettingsClass</code> <code>pmx_settings</code></dd>
<dt>vpc</dt>
<dd>[Optional] <code>logical</code> a boolean indiacting if vpc should be calculated (by default <code>TRUE</code>)</dd></dl>

Arguments

Creates pmx controller from  an nlimxr fit object — pmx_nlmixr

<dl>

<dt>fit</dt>
<dd>nlmixr object</dd>


<dt>dvid</dt>
<dd>[Optional] <code>character</code> observation type parameter.</dd>


<dt>conts</dt>
<dd>[Optional]<code>character</code> vector of continuous covariates</dd>


<dt>cats</dt>
<dd>[Optional]<code>character</code> vector of categorical covariates</dd>


<dt>strats</dt>
<dd>[Optional]<code>character</code> extra stratification variables</dd>


<dt>endpoint</dt>
<dd><code>pmxEndpointClass</code> or <code>integer</code> or <code>charcater</code> defalut to NULL
of the endpoint code. <code>pmx_endpoint</code></dd>


<dt>settings</dt>
<dd>[Optional]<code>pmxSettingsClass</code> <code>pmx_settings</code></dd>


<dt>vpc</dt>
<dd>[Optional] <code>logical</code> a boolean indiacting if vpc should be calculated (by default <code>TRUE</code>)</dd>

</dl>

pmx_nlmixr: Creates pmx controller from an nlimxr fit object

Description

Usage

Value

Arguments