grandR (version 0.2.6)

Analyses: Analysis table functions

Description

Get analysis names and add or remove analyses

Usage

Analyses(data, description = FALSE)
AddAnalysis(
  data,
  name,
  table,
  by = NULL,
  warn.present = TRUE,
  warn.genes = TRUE
)
DropAnalysis(data, pattern = NULL)

Value

Either the analysis names or a grandR data with added/removed slots or the metatable to be used with AddAnalysis

Arguments

data

A grandR object

description

if TRUE, also return the column names of each analysis table (i.e. a list named according to the analyses)

name

The user-defined analysis name

table

The analysis table to add

by

Specify a column that contains gene names or symbols (see details)

warn.present

Warn if an analysis with the same name is already present (and then overwrite)

warn.genes

Warn if genes are missing (and then add NA)

pattern

A regular expression that is matched to analysis names

Functions

• Analyses(): Obtain the analyses names

• AddAnalysis(): Add an analysis table

• DropAnalysis(): Remove analyses from the grandR object

Details

The columns in the analysis tables are defined by the analysis method (e.g. "Synthesis","Half-life" and "rmse" by FitKinetics). A call to an analysis function might produce more than one table (e.g. because kinetic modeling is done for multiple Conditions). In this case, AddAnalysisTable produces more than one analysis table.

AddAnalysis is in most cases not called directly by the user, but is used by analysis methods to add their final result to a grandR object (e.g., FitKinetics,LikelihoodRatioTest,LFC,PairwiseDESeq2).

If it is called by the user (e.g. to add analysis results from external tools or from the literature, see pulse-chase vignette), then the user must make sure that either the rownames of the given table can be recognized as genes (names or symbols), or that there is a column in the table giving genes (this must be specified as the "by" parameter). The table does neither have to be sorted the same way the grandR object is, nor does it have to be complete. AddAnalysis will take care or reordering and inserting NA for missing genes (and it will issue a warning in case of missing genes).

See Also

Slots, DefaultSlot

Examples

sars <- ReadGRAND(system.file("extdata", "sars.tsv.gz", package = "grandR"),
                  design=c("Cell",Design$dur.4sU,Design$Replicate))

sars <- Normalize(sars)     # default behavior is to update the default slot; this calls AddSlot
Slots(sars)
DefaultSlot(sars)
sars <- DropSlot(sars,"norm")
sars                        # note that the default slot reverted to count