Sachs

<p>Data concerning protein expression levels in human immune system
    cells under stimulations.</p>

datasets

A comprehensive package for structural multivariate
function estimation using smoothing splines.

Chong Gu

General Smoothing Splines

Sachs function

<p>A data frame containing 7466 cells, with flow cytometry measurements
    of 11 phosphorylated proteins and phospholipids, on the <code>log10</code>
    scale of the original.</p><table class="table">
<tr><td><code>praf</code></td><td>Raf phosphorylated at S259.</td></tr>
<tr><td><code>pmek</code></td><td>Mek1/mek2 phosphorylated at S217/S221.</td></tr>
<tr><td><code>plcg</code></td><td>Phosphorylation of phospholipase \(C-\gamma\)
	on Y783.</td></tr>
<tr><td><code>pip2</code></td><td>Phophatidylinositol 4,5-biphosphate.</td></tr>
<tr><td><code>pip3</code></td><td>Phophatidylinositol 3,4,5-triphosphate.</td></tr>
<tr><td><code>p44.42</code></td><td>Erk1/erk2 phosphorylated at T202/Y204.</td></tr>
<tr><td><code>pakts473</code></td><td>AKT phosphorylated at S473.</td></tr>
<tr><td><code>pka</code></td><td>Phosphorylation of of protein kinase A
	substrates on 3 sites.</td></tr>
<tr><td><code>pkc</code></td><td>Phosphorylation of of protein kinase C
	substrates on S660.</td></tr>
<tr><td><code>p38</code></td><td>Erk1/erk2 phosphorylated at T180/Y182.</td></tr>
<tr><td><code>pjnk</code></td><td>Erk1/erk2 phosphorylated at T183/Y185.</td></tr>
</table><p></p><p></p>

Format

Protein Expression in Human Immune System Cells — Sachs

<p>A data frame containing 7466 cells, with flow cytometry measurements
    of 11 phosphorylated proteins and phospholipids, on the <code>log10</code>
    scale of the original.</p><table class='table'>
<tr><td><code>praf</code></td><td>Raf phosphorylated at S259.</td></tr>
<tr><td><code>pmek</code></td><td>Mek1/mek2 phosphorylated at S217/S221.</td></tr>
<tr><td><code>plcg</code></td><td>Phosphorylation of phospholipase \(C-\gamma\)
	on Y783.</td></tr>
<tr><td><code>pip2</code></td><td>Phophatidylinositol 4,5-biphosphate.</td></tr>
<tr><td><code>pip3</code></td><td>Phophatidylinositol 3,4,5-triphosphate.</td></tr>
<tr><td><code>p44.42</code></td><td>Erk1/erk2 phosphorylated at T202/Y204.</td></tr>
<tr><td><code>pakts473</code></td><td>AKT phosphorylated at S473.</td></tr>
<tr><td><code>pka</code></td><td>Phosphorylation of of protein kinase A
	substrates on 3 sites.</td></tr>
<tr><td><code>pkc</code></td><td>Phosphorylation of of protein kinase C
	substrates on S660.</td></tr>
<tr><td><code>p38</code></td><td>Erk1/erk2 phosphorylated at T180/Y182.</td></tr>
<tr><td><code>pjnk</code></td><td>Erk1/erk2 phosphorylated at T183/Y185.</td></tr>
</table>



Sachs: Protein Expression in Human Immune System Cells

Description

Usage

Arguments

Format

`praf`	Raf phosphorylated at S259.
`pmek`	Mek1/mek2 phosphorylated at S217/S221.
`plcg`	Phosphorylation of phospholipase \(C-\gamma\) on Y783.
`pip2`	Phophatidylinositol 4,5-biphosphate.
`pip3`	Phophatidylinositol 3,4,5-triphosphate.
`p44.42`	Erk1/erk2 phosphorylated at T202/Y204.
`pakts473`	AKT phosphorylated at S473.
`pka`	Phosphorylation of of protein kinase A substrates on 3 sites.
`pkc`	Phosphorylation of of protein kinase C substrates on S660.
`p38`	Erk1/erk2 phosphorylated at T180/Y182.
`pjnk`	Erk1/erk2 phosphorylated at T183/Y185.