Data concerning mouse embryonic stem cell gene expression and transcription factor association strength.
data(esc)
A data frame containing 1027 genes with the following variables.
y1 | Gene expression after 4 days. |
y2 | Gene expression after 8 days. |
y3 | Gene expression after 14 days. |
klf4 | Score of TFAS with KLF4. |
nanog | Score of TFAS with NANOG. |
oct4 | Score of TFAS with OCT4. |
sox2 | Score of TFAS with SOX2. |
clusterID | Cluster identification. |
Cai, J., Xie, D., Fan, Z., Chipperfield, H., Marden, J., Wong, W. H., and Zhong, S. (2010), Modeling co-expression across species for complex traits: insights to the difference of human and mouse embryonic stem cells. PLoS Computational Biology, 6, e1000707.
Ouyang, Z., Zhou, Q., and Wong, W. H. (2009), chip-seq of transcription factors predicts absolute and differential gene expression in embryonic stem cells. Proceedings of the National Academy of Sciences of USA, 106, 21521--21526.