age_draw_smooth

Gender. Either 'Male' or 'Female'.

Race/ethnicity. One of 'Mexican American', 'Other Hispanic', 
'Non-Hispanic Black', 'Non-Hispanic White', 'Other'.

nsamp

Two-element numeric vector giving the minimum and 
maximum ages in months to include.

agelim_months

Draws ages from a smoothed distribution for a given gender/race combination

Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") using data obtained from relatively high throughput, in vitro studies. Both physiologically-based ("PBTK") and empirical (e.g., one compartment) "TK" models can be parameterized for several hundred chemicals and multiple species. These models are solved efficiently, often using compiled (C-based) code. A Monte Carlo sampler is included for simulating biological variability and measurement limitations. Functions are also provided for exporting "PBTK" models to "SBML" and "JARNAC" for use with other simulation software. These functions and data provide a set of tools for in vitro-in vivo extrapolation ("IVIVE") of high throughput screening data (e.g., ToxCast) to real-world exposures via reverse dosimetry (also known as "RTK").

age_draw_smooth: Draws ages from a smoothed distribution for a given gender/race combination

Description

Usage

Arguments

Value

References