blood_mass_correct

A vector of blood masses in kg to be replaced with averages.

blood_mass

age_months

age_years

A vector of genders (either 'Male' or 'Female').

gender

weight

If blood mass from <code><a rd-options="" href="/link/blood_weight?package=httk&version=1.8" data-mini-rdoc="httk::blood_weight">blood_weight</a></code> is negative or very small, then
just default to the mean blood mass by age. (Geigy Scientific Tables, 7th ed.)

Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") using data obtained from relatively high throughput, in vitro studies. Both physiologically-based ("PBTK") and empirical (e.g., one compartment) "TK" models can be parameterized for several hundred chemicals and multiple species. These models are solved efficiently, often using compiled (C-based) code. A Monte Carlo sampler is included for simulating biological variability and measurement limitations. Functions are also provided for exporting "PBTK" models to "SBML" and "JARNAC" for use with other simulation software. These functions and data provide a set of tools for in vitro-in vivo extrapolation ("IVIVE") of high throughput screening data (e.g., ToxCast) to real-world exposures via reverse dosimetry (also known as "RTK").

John Wambaugh

httk

High-Throughput Toxicokinetics

blood_mass_correct function

If blood mass from <code><a rd-options='' href='blood_weight'>blood_weight</a></code> is negative or very small, then
just default to the mean blood mass by age. (Geigy Scientific Tables, 7th ed.)

blood_mass_correct: Find average blood masses by age.

Description

Usage

Arguments

Value

References