r_left_censored_norm

Mean of censored distribution. Default 0.

mean

Standard deviation of censored distribution. Default 1.

Bound below which to censor. Default 0.005.

Lower bound on censored distribution. Default 0.

lower

Upper bound on censored distribution. Default 1.

upper

Returns draws from a normal distribution with a lower censoring limit of lod
(limit of detection)

Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") using data obtained from relatively high throughput, in vitro studies. Both physiologically-based ("PBTK") and empirical (e.g., one compartment) "TK" models can be parameterized for several hundred chemicals and multiple species. These models are solved efficiently, often using compiled (C-based) code. A Monte Carlo sampler is included for simulating biological variability and measurement limitations. Functions are also provided for exporting "PBTK" models to "SBML" and "JARNAC" for use with other simulation software. These functions and data provide a set of tools for in vitro-in vivo extrapolation ("IVIVE") of high throughput screening data (e.g., ToxCast) to real-world exposures via reverse dosimetry (also known as "RTK").

r_left_censored_norm: Returns draws from a normal distribution with a lower censoring limit of lod (limit of detection)

Description

Usage

Arguments

Value