Charts giving weight-for-length percentiles for boys and girls under age 2.

datasets

Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") using data obtained from relatively high throughput, in vitro studies. Both physiologically-based ("PBTK") and empirical (e.g., one compartment) "TK" models can be parameterized for several hundred chemicals and multiple species. These models are solved efficiently, often using compiled (C-based) code. A Monte Carlo sampler is included for simulating biological variability and measurement limitations. Functions are also provided for exporting "PBTK" models to "SBML" and "JARNAC" for use with other simulation software. These functions and data provide a set of tools for in vitro-in vivo extrapolation ("IVIVE") of high throughput screening data (e.g., ToxCast) to real-world exposures via reverse dosimetry (also known as "RTK").

John Wambaugh

httk

High-Throughput Toxicokinetics

wfl function

A data.table object with variables<dl class="dl-horizontal">
<dt><code>Sex</code></dt><dd>'Male'
 or 'Female'</dd> <dt><code>Length</code></dt><dd>length in cm</dd> <dt><code>L</code>, <code>M</code>,
 <code>S</code></dt><dd>LMS parameters; see 
 <a href="/link/www.cdc.gov%2Fgrowthcharts%2Fpercentile_data_files.htm?package=httk&version=1.8" data-mini-rdoc="httk::www.cdc.gov/growthcharts/percentile_data_files.htm">www.cdc.gov/growthcharts/percentile_data_files.htm</a></dd> <dt><code>P2.3</code>,
 <code>P5</code>, <code>P10</code>, <code>P25</code>, <code>P50</code>, <code>P75</code>, <code>P90</code>,
 <code>P95</code>, and <code>P97.7</code></dt><dd>weight percentiles</dd> </dl>

Format

WHO weight-for-length charts — wfl

A data.table object with variables<dl class='dl-horizontal'>
<dt><code>Sex</code></dt><dd>'Male'
 or 'Female'</dd> <dt><code>Length</code></dt><dd>length in cm</dd> <dt><code>L</code>, <code>M</code>,
 <code>S</code></dt><dd>LMS parameters; see 
 <a href='www.cdc.gov/growthcharts/percentile_data_files.htm'>www.cdc.gov/growthcharts/percentile_data_files.htm</a></dd> <dt><code>P2.3</code>,
 <code>P5</code>, <code>P10</code>, <code>P25</code>, <code>P50</code>, <code>P75</code>, <code>P90</code>,
 <code>P95</code>, and <code>P97.7</code></dt><dd>weight percentiles</dd> </dl>

wfl: WHO weight-for-length charts

Description

Usage

Arguments

Format

Details