A549_1

A549_2

Calu1_1

Calu1_2

H322_1

H322_2

HCC2429_1

HCC2429_2


  For purpose of computational, lesion-based prediction of compound
  activity in 84 non-small cell lung cancer (NSCLC) cell lines, these
  were treated with a selection of compounds to measure the respective
  concentration where 50 per cent of cell growth was inhibited after a
  predefined time period. Most of the screening experiments were
  performed on 384 (16 x 24)-well plates, were the experimental setup was
  designed according to the arrangement in the files
  <code>"mpi384_measure.txt"</code>, <code>"mpi384_control.txt"</code> and
  <code>"mpi384_dilution.txt"</code> that are installed together with the
  package.<p></p><p>  These data sets are the direct output from a signal reader of the
  384-well plates for the A549, Calu1, H322 and H2429 cancer cell lines
  selected from the 84 NSCLC cell lines collection. A tab-delimited version
  is installed together with the package.
</p>

datasets

nsclc

Calculation of IC50 values, automatic drawing of
dose-response curves and validation of compound screens on 96-
and 384-well plates.

nsclc: Results from a compound screen on 84 NSCLC cell lines.

Description

Arguments

References