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kernel
pathway
An object of class lkmt containing exemplary test results for an application of the logistic kernel machine test, derived from the example data.
lkmt
data(lkmt.net.kernel.hsa04020)
An object of class lkmt for the network-based kernel and the pathway hsa04020.
gives a formular defining the nullmodel used in the logistic kernel machine test
includes the kernel object of the pathway to be evaluated
gives the GWASdata object including the study data considered in testing
GWASdata
gives the value of the test statistic
specifies the degrees of freedom
includes teh p-value resulting from the test
data(hsa04020) data(gwas) net_kernel <- calc_kernel(gwas, hsa04020, knots=NULL, type='net', calculation='cpu') lkmt_test(pheno ~ sex + age, net_kernel, gwas, method='satt')
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