serotonin


This simulated data mimics a PET imaging study where the 5-HT2A
receptor and serotonin transporter (SERT) binding potential has
been quantified into 8 different regions. The 5-HT2A
cortical regions are considered high-binding regions
measurements.  These measurements can be regarded as proxy measures of
the extra-cellular levels of serotonin in the brain
<table><tr><td>
        day    </td>
<td> numeric </td>
</tr><tr><td> Scan day of the year </td>
<td>
        age    </td>
</tr><tr><td> numeric </td>
<td> Age at baseline scan </td>
</tr><tr><td>
        mem    </td>
<td> numeric </td>
</tr><tr><td> Memory performance score </td>
<td>
        depr   </td>
</tr><tr><td> numeric </td>
<td> Depression (mild) status 500 days after baseline </td>
</tr><tr><td>
        gene1  </td>
<td> numeric </td>
</tr><tr><td> Gene marker 1 (HTR2A) </td>
<td>
        gene2  </td>
</tr><tr><td> numeric </td>
<td> Gene marker 2 (HTTTLPR) </td>
</tr><tr><td>
        cau </td>
<td> numeric </td>
</tr><tr><td> SERT binding, Caudate Nucleus </td>
<td>
        th  </td>
</tr><tr><td> numeric </td>
<td> SERT binding, Thalamus </td>
</tr><tr><td>
        put </td>
<td> numeric </td>
</tr><tr><td> SERT binding, Putamen </td>
<td>
        mid </td>
</tr><tr><td> numeric </td>
<td> SERT binding, Midbrain </td>
</tr><tr><td>
        aci </td>
<td> numeric </td>
</tr><tr><td> 5-HT2A binding, Anterior cingulate gyrus </td>
<td>
        pci  </td>
</tr><tr><td> numeric </td>
<td> 5-HT2A binding, Posterior cingulate gyrus </td>
</tr><tr><td>
        sfc </td>
<td> numeric </td>
</tr><tr><td> 5-HT2A binding, Superior frontal cortex </td>
<td>
        par </td>
</tr><tr><td> numeric </td>
<td> 5-HT2A binding, Parietal cortex </td>
</tr></table>


datasets

Estimation and simulation of latent variable models.

Klaus K Holst

lava

serotonin: Serotonin data

Description

Arguments

Format

Source

day	numeric
Scan day of the year	age
numeric	Age at baseline scan
mem	numeric
Memory performance score	depr
numeric	Depression (mild) status 500 days after baseline
gene1	numeric
Gene marker 1 (HTR2A)	gene2
numeric	Gene marker 2 (HTTTLPR)
cau	numeric
SERT binding, Caudate Nucleus	th
numeric	SERT binding, Thalamus
put	numeric
SERT binding, Putamen	mid
numeric	SERT binding, Midbrain
aci	numeric
5-HT2A binding, Anterior cingulate gyrus	pci
numeric	5-HT2A binding, Posterior cingulate gyrus
sfc	numeric
5-HT2A binding, Superior frontal cortex	par
numeric	5-HT2A binding, Parietal cortex