ldlasso (version 3.2)

ldlasso-package: LD LASSO for Case Control Genetic Association Study

Description

Performs a modification of the fused LASSO for SNP subset selection in genetic association studies. The LD LASSO requires densely spaced SNP data and haplotype block structure.

Details

The ldlasso package is a collection of functions designed to apply the LD LASSO methodology as described in Younkin and Rao 2010. Functions usesful for displaying the results are also included.

Package:

ldlasso

Version:

2.0

Date:

February 1, 2011

References

Samuel Younkin, Joseph Nadeau, Robert Elston and J. Sunil Rao, "The Linkage Disequilibrium LASSO for SNP Selection in a Genetic Association Study of Late Onset Alzheimer Disease," Technical Report, 2010

See Also

ld_lasso_method, ld_lasso, plot_ldlasso, plot_beta, heatmap

Examples

  # Load example data
  data(ldlasso_example)
  ls()

  plot_ldlasso( ldlasso.obj )

  heatmap(ldlasso.obj)