mQTL.NMR (version 1.6.0)

SRV: Statistical Recoupling of Variables

Description

Base function for dimensionality reduction by statistical recoupling of variables

Usage

SRV(X, minsize, correl, clustf = median)

Arguments

X

matrix of metabolomic data

minsize

a numerical value defining the singlet size

correl

a numerical value defining the bucketting resolution

clustf

a numerical value defining the correlation threshold

Value

A list:

indicesdebf

a vector indicating the starting border of superclusters

indicesfinf

a vector indicating the ending border of superclusters

Xcluster

matrix of reduced data

References

Blaise,B. et al (2009) Statistical recoupling prior to significance testing in nuclear magnetic resonance based metabonomics, Anal. Chem., 81(15), 6242-6251.

See Also

pre_mQTL

Examples

# Load data files

    load_datafiles()

    Sp<-read.table(phenofile, as.is=TRUE, header=TRUE, sep='\t')

# Perform the SRV analysis to reduce the number of dimension of Spectra #data (Sp)

    corrT=0.9 # correlation threshold
    minsize=10 # singlet size
    met="rectangle" # summary measure

    SRV<-SRV(t(Sp), minsize, corrT,clustf=met)