mixAK (version 5.4)

Enzyme: Enzymatic activity in the blood

Description

Enzymatic activity in the blood, for an enzyme involved in the metabolism of carcinogenic substances, among a group of 245 unrelated individuals.

Bechtel et al. (1993) identified a mixture of two skewed distributions by using maximum-likelihood estimation. Richardson and Green (1997) used a normal mixture estimated using reversible jump MCMC to estimate the distribution of the enzymatic activity.

Usage

data(Enzyme)

Format

A numeric vector with observed values.

References

\(\mbox{Bechtel, Y. C., Bona\"{\i}ti-Pelli\'e, C., Poisson, N., Magnette, J., and Bechtel, P. R.}\)(1993). A population and family study of N-acetyltransferase using caffeine urinary metabolites. Clinical Pharmacology and Therapeutics, 54, 134--141.

Richardson, S. and Green, P. J. (1997). On Bayesian analysis of mixtures with unknown number of components (with Discussion). Journal of the Royal Statistical Society, Series B, 59, 731--792.

Examples

data(Enzyme)
summary(Enzyme)