data(vac18.simulated)
The simulation study was based on a mixed effects model (see reference for details). Ten clusters of 100 genes were generated. Amongt those, 4 clusters of genes discriminate the 4 stimulations (denoted LIPO5, GAG+, GAG- and NS) as follows: \ -2 gene clusters discriminate (LIPO5, GAG+) versus (GAG-, NS) \ -2 gene clusters discriminate LIPO5 versus GAG+, while GAG+ and NS have the same effect \ -2 gene clusters discriminate GAG- versus NS, while LIPO5 and GAG+ have the same effect \ -the 4 remaining clusters represent noisy signal (no stimulation effect)