# NOT RUN {
## validation for objects of class 'splsda'
# }
# NOT RUN {
data(breast.tumors)
X = breast.tumors$gene.exp
Y = as.factor(breast.tumors$sample$treatment)
out = tune.splsda(X, Y, ncomp = 3, nrepeat = 2, logratio = "none",
test.keepX = c(5, 10, 15), folds = 10, dist = "max.dist",
progressBar = TRUE)
plot(out)
# }
# NOT RUN {
## validation for objects of class 'mint.splsda'
# }
# NOT RUN {
data(stemcells)
data = stemcells$gene
type.id = stemcells$celltype
exp = stemcells$study
out = tune(method="mint.splsda", X=data,Y=type.id, ncomp=2, study=exp, test.keepX=seq(1,10,1))
out$choice.keepX.constraint
plot(out)
# }
# NOT RUN {
## validation for objects of class 'mint.splsda'
# }
# NOT RUN {
data("breast.TCGA")
# this is the X data as a list of mRNA and miRNA; the Y data set is a single data set of proteins
data = list(mrna = breast.TCGA$data.train$mrna, mirna = breast.TCGA$data.train$mirna,
protein = breast.TCGA$data.train$protein)
# set up a full design where every block is connected
# could also consider other weights, see our mixOmics manuscript
design = matrix(1, ncol = length(data), nrow = length(data),
dimnames = list(names(data), names(data)))
diag(design) = 0
design
# set number of component per data set
ncomp = 5
# Tuning the first two components
# -------------
# definition of the keepX value to be tested for each block mRNA miRNA and protein
# names of test.keepX must match the names of 'data'
test.keepX = list(mrna = seq(10,40,20), mirna = seq(10,30,10), protein = seq(1,10,5))
# the following may take some time to run, note that for through tuning
# nrepeat should be > 1
tune = tune.block.splsda(X = data, Y = breast.TCGA$data.train$subtype,
ncomp = ncomp, test.keepX = test.keepX, design = design, nrepeat = 3)
tune$choice.ncomp
tune$choice.keepX
plot(tune)
# }
# NOT RUN {
# }
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