The function performs the regularized extension of the Canonical Correlation Analysis to seek correlations between two data matrices.
rcc(X,
Y,
ncomp = 2,
method = "ridge", #choose between c("ridge", "shrinkage")
lambda1 = 0,
lambda2 = 0)numeric matrix or data frame \((n \times p)\), the observations on the \(X\) variables.
NAs are allowed.
numeric matrix or data frame \((n \times q)\), the observations on the \(Y\) variables.
NAs are allowed.
One of "ridge" or "shrinkage". If "ridge", lambda1 and lambda2 need to be supplied (see also our function tune.rcc); if "shrinkage", parameters are directly estimated with Strimmer's formula, see below and reference.
the number of components to include in the model. Default to 2.
a non-negative real. The regularization parameter for the X and
Y data. Defaults to lambda1=lambda2=0. Only used if method="ridge"
rcc returns a object of class "rcc", a list that
contains the following components:
the original \(X\) data.
the original \(Y\) data.
a vector containing the canonical correlations.
a vector containing the regularization parameters whether those were input if ridge method or directly estimated with the shrinkage method.
list containing the estimated coefficients used to calculate the canonical variates in \(X\) and \(Y\).
list containing the canonical variates.
list containing the names to be used for individuals and variables.
The main purpose of Canonical Correlations Analysis (CCA) is the exploration of sample correlations between two sets of variables \(X\) and \(Y\) observed on the same individuals (experimental units) whose roles in the analysis are strictly symmetric.
The cancor function performs the core of computations
but additional tools are required to deal with data sets highly
correlated (nearly collinear), data sets with more variables
than units by example.
The rcc function, the regularized version of CCA,
is one way to deal with this problem by
including a regularization step in the computations of CCA.
Such a regularization in this context
was first proposed by Vinod (1976), then developped by Leurgans et al. (1993).
It consists in the regularization of the empirical covariances matrices of
\(X\) and \(Y\) by adding a multiple of the matrix identity, that is,
Cov\((X)+ \lambda_1 I\) and Cov\((Y)+ \lambda_2 I\).
When lambda1=0 and lambda2=0, rcc performs a classical
CCA, if possible (i.e. when \(n > p+q\).
The shrinkage estimates method = "shrinkage" can be used to bypass tune.rcc to choose the shrinkage parameters - which can be long and costly to compute with very large data sets. Note that both functions tune.rcc (which uses cross-validation) and the whrinkage parameters (which uses the formula from Schafer and Strimmer) may output different results.
Note: when method = "shrinkage" the input data are centered and scaled for the estimation of the shrinkage parameters and the calculation of the regularised variance-covariance matrices in rcc.
The estimation of the missing values can be performed
by the reconstitution of the data matrix using the nipals function. Otherwise, missing
values are handled by casewise deletion in the rcc function.
Gonz<U+00E1>lez, I., D<U+00E9>jean, S., Martin, P. G., and Baccini, A. (2008). CCA: An R package to extend canonical correlation analysis. Journal of Statistical Software, 23(12), 1-14.
Gonz<U+00E1>lez, I., D<U+00E9>jean, S., Martin, P., Goncalves, O., Besse, P., and Baccini, A. (2009). Highlighting relationships between heterogeneous biological data through graphical displays based on regularized canonical correlation analysis. Journal of Biological Systems, 17(02), 173-199.
Leurgans, S. E., Moyeed, R. A. and Silverman, B. W. (1993). Canonical correlation analysis when the data are curves. Journal of the Royal Statistical Society. Series B 55, 725-740.
Vinod, H. D. (1976). Canonical ridge and econometrics of joint production. Journal of Econometrics 6, 129-137.
Opgen-Rhein, R., and K. Strimmer. 2007. Accurate ranking of differentially expressed genes by a distribution-free shrinkage approach. Statist. emphAppl. Genet. Mol. Biol. 6:9. (http://www.bepress.com/sagmb/vol6/iss1/art9/)
Sch"afer, J., and K. Strimmer. 2005. A shrinkage approach to large-scale covariance estimation and implications for functional genomics. Statist. emphAppl. Genet. Mol. Biol. 4:32. (http://www.bepress.com/sagmb/vol4/iss1/art32/)
summary, tune.rcc,
plot.rcc, plotIndiv,
plotVar, cim, network and http://www.mixOmics.org for more details.
# NOT RUN {
## Classic CCA
data(linnerud)
X <- linnerud$exercise
Y <- linnerud$physiological
linn.res <- rcc(X, Y)
## Regularized CCA
data(nutrimouse)
X <- nutrimouse$lipid
Y <- nutrimouse$gene
nutri.res1 <- rcc(X, Y, ncomp = 3, lambda1 = 0.064, lambda2 = 0.008)
## using shrinkage parameters
nutri.res2 <- rcc(X, Y, ncomp = 3, method = 'shrinkage')
nutri.res2$lambda # the shrinkage parameters
# }
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