NCI60_4arrays:
Microarray gene expression profiles of the NCI 60 cell lines from
4 different platforms
Description
The 60 human tumour cell lines are derived
from patients with leukaemia, melanoma, lung, colon, central
nervous system, ovarian, renal, breast and prostate cancers. The cell line
panel is widely used in anti-cancer drug screen. In this dataset,
a subset of microarray gene expression of the NCI 60 cell lines from
four different platforms are combined in a list, which could be used as
input to mcia directly.
Value
NCI60_4arrays will be loaded in your working space.
Format
The format is: List of 4 data.frames
- \$agilent:
data.frame containing 300 rows and 60 columns.
300 gene expression log ratio measurements of the NCI60 cell lines, by Agilent
platform.
- \$hgu133:
data.frame containing 298 rows and 60 columns.
298 gene expression log ratio measurements of the NCI60 cell lines, by H-GU133
platform.
- \$hgu133p2:
data.frame containing 268 rows and 60 columns.
268 gene expression log ratio measurements of the NCI60 cell lines, by H-GU133
plus 2.0 platform.
- \$hgu95:
data.frame containing 288 rows and 60 columns.
288 gene expression log ratio measurements of the NCI60 cell lines, by H-GU95
platform.
References
Reinhold WC, Sunshine M, Liu H, Varma S, Kohn KW, Morris J, Doroshow J, Pommier Y
CellMiner: A Web-Based Suite of Genomic and Pharmacologic Tools
to Explore Transcript and Drug Patterns in the NCI-60 Cell Line Set.
Cancer Research. 2012 Jul, 15;72(14):3499-511