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morse (version 3.3.4)

survFitTT.survDataCstExp: Fits a Bayesian concentration-response model for target-time survival analysis

Description

This function estimates the parameters of an concentration-response model for target-time survival analysis using Bayesian inference. In this model, the survival rate of individuals at a given time point (called target time) is modeled as a function of the chemical compound concentration. The actual number of surviving individuals is then modeled as a stochastic function of the survival rate. Details of the model are presented in the vignette accompanying the package.

Usage

# S3 method for survDataCstExp
survFitTT(
  data,
  target.time = NULL,
  lcx = c(5, 10, 20, 50),
  n.chains = 3,
  quiet = FALSE,
  ...
)

Value

The function returns an object of class survFitTT, which is a list with the following information:

estim.LCx

a table of the estimated \(LC_x\) along with their 95% credible intervals

estim.par

a table of the estimated parameters (medians) and 95% credible intervals

det.part

the name of the deterministic part of the used model

mcmc

an object of class mcmc.list with the posterior distribution

warnings

a table with warning messages

model

a JAGS model object

parameters

a list of parameter names used in the model

n.chains

an integer value corresponding to the number of chains used for the MCMC computation

n.iter

a list of two indices indicating the beginning and the end of monitored iterations

n.thin

a numerical value corresponding to the thinning interval

jags.data

a list of the data passed to the JAGS model

transformed.data

the survData object passed to the function

dataTT

the dataset with which the parameters are estimated

Arguments

data

an object of class survData

target.time

the chosen endpoint to evaluate the effect of the chemical compound concentration, by default the last time point available for all concentrations

lcx

desired values of \(x\) (in percent) for which to compute \(LC_x\).

n.chains

number of MCMC chains, the minimum required number of chains is 2

quiet

if TRUE, does not print messages and progress bars from JAGS

...

Further arguments to be passed to generic methods

Details

The function returns parameter estimates of the concentration-response model and estimates of the so-called \(LC_x\), that is the concentration of chemical compound required to get an \((1 - x/100)\) survival rate.