nlme (version 3.1-114)

Cefamandole: Pharmacokinetics of Cefamandole

Description

The Cefamandole data frame has 84 rows and 3 columns.

source

Pinheiro, J. C. and Bates, D. M. (2000), Mixed-Effects Models in S and S-PLUS, Springer, New York. (Appendix A.4)

Davidian, M. and Giltinan, D. M. (1995), Nonlinear Models for Repeated Measurement Data, Chapman and Hall, London.

Details

Davidian and Giltinan (1995, 1.1, p. 2) describe data obtained during a pilot study to investigate the pharmacokinetics of the drug cefamandole. Plasma concentrations of the drug were measured on six healthy volunteers at 14 time points following an intraveneous dose of 15 mg/kg body weight of cefamandole.

Examples

plot(Cefamandole)
fm1 <- nlsList(SSbiexp, data = Cefamandole)
summary(fm1)