A model function for a model used with the Phenobarb data.
This function uses compiled C code to improve execution speed.
phenoModel(Subject, time, dose, lCl, lV)a numeric vector of predicted phenobarbital concentrations.
an integer vector of subject identifiers. These should be sorted in increasing order.
numeric. A vector of the times at which the sample was drawn or the drug administered (hr).
numeric. A vector of doses of drug administered (\(u\)g/kg).
numeric. A vector of values of the natural log of the
clearance parameter according to Subject and time.
numeric. A vector of values of the natural log of the
effective volume of distribution according to Subject and
time.
José Pinheiro and Douglas Bates bates@stat.wisc.edu
See the details section of Phenobarb for a description
of the model function that phenoModel evaluates.
Pinheiro, J. C. and Bates, D. M. (2000) Mixed-effects Models in S and S-PLUS, Springer. (section 6.4)