npdeSimData

This function is used to create a NpdeSimData object containing the simulated data corresponding to an NpdeData object

Provides routines to compute normalised prediction distribution errors, a metric designed to evaluate non-linear mixed effect models such as those used in pharmacokinetics and pharmacodynamics.

Emmanuelle Comets

npde

Normalised Prediction Distribution Errors for Nonlinear
Mixed-Effect Models

Karl Brendel

Thi Huyen Tram Nguyen

Marc Cerou

Romain Leroux

France Mentre

npdeSimData function

<dl><dt>npde.data</dt>
<dd>a NpdeData object</dd>
<dt>name.simdata</dt>
<dd>name of the file containing the simulated data, or a dataframe containing it</dd>
<dt>header</dt>
<dd>boolean indicating whether the file has a header (a header is 
mandatory if detect is TRUE)</dd>
<dt>sep</dt>
<dd>field separator (for files on disk)</dd>
<dt>na.strings</dt>
<dd>strings to be considered as indicating NA</dd>
<dt>detect</dt>
<dd>a boolean controlling whether automatic recognition of columns in the dataset is on, defaults to FALSE
if FALSE, the first 3 columns of the simulated data file will will be used as simulated id, predictor and response respectively
if TRUE, the function will look for columns named respectively idsim, xsim and ysim (it will fail with an error message if these columns
are not present in the simulated data)</dd>
<dt>verbose</dt>
<dd>whether to print warning messages, defaults to FALSE (set to TRUE to check how data is being handled)</dd></dl>

Arguments

Emmanuelle Comets &lt;emmanuelle.comets@bichat.inserm.fr&gt;

Author

Creates a NpdeSimData object — npdeSimData

<dl>

<dt>npde.data</dt>
<dd>a NpdeData object</dd>


<dt>name.simdata</dt>
<dd>name of the file containing the simulated data, or a dataframe containing it</dd>


<dt>header</dt>
<dd>boolean indicating whether the file has a header (a header is 
mandatory if detect is TRUE)</dd>


<dt>sep</dt>
<dd>field separator (for files on disk)</dd>


<dt>na.strings</dt>
<dd>strings to be considered as indicating NA</dd>


<dt>detect</dt>
<dd>a boolean controlling whether automatic recognition of columns in the dataset is on, defaults to FALSE
if FALSE, the first 3 columns of the simulated data file will will be used as simulated id, predictor and response respectively
if TRUE, the function will look for columns named respectively idsim, xsim and ysim (it will fail with an error message if these columns
are not present in the simulated data)</dd>


<dt>verbose</dt>
<dd>whether to print warning messages, defaults to FALSE (set to TRUE to check how data is being handled)</dd>

</dl>

npdeSimData: Creates a NpdeSimData object

Description

Usage

Value

Arguments

Author

See Also