plotBindingPotential: Plot Baseline Versus Post-Treatment Binding Potentials

Description

Inspired by the Lassen plot (Cunningham et al., 2010) this is a straightforward graphical summary of pre-treatment versus post-treatment binding potentials for a single subject across multiple brain regions.

Usage

plotBindingPotential(
  base,
  drug,
  lty45 = 2,
  lty = 1,
  lwd45 = 2,
  lwd = 3,
  col45 = "darkgrey",
  col = "orange",
  pch = 1,
  cex = 1,
  xlim = range(0, base, 0.5),
  ylim = range(0, drug, 0.5),
  xlab = expression(BP[ND]^{
     Base
 }),
  ylab = expression(BP[ND]^{
     Drug
 }),
  ...
)

Value

A plot is shown, NULL is returned

Arguments

base: is the vector of baseline binding potentials across brain regions.
drug: is the vector of post-treatment binding potentials across brain regions.
lty45: is the line type for the 45-degree line.
lty: is the line type for the estimated regression line.
lwd45: is the line width for the 45-degree line.
lwd: is the line width for the estimated regression line.
col45: is the color for the 45-degree line.
col: is the color for the estimated regression line.
pch: is the plotting character symbol.
cex: is the size of the plotting symbol.
xlim: is the range of values on the x-axis.
ylim: is the range of values on the y-axis.
xlab: is the label on the x-axis.
ylab: is the label on the y-axis.
...: additional arguments to be passed to the plot function.

Author

Brandon Whitcher bwhitcher@gmail.com

Details

See the reference below.

References

Cunningham VJ, Rabiner EA, Slifstein M, Laruelle M (2010). Measuring drug occupancy in the absence of a reference region: the Lassen plot re-visited, Journal of Cerebral Blood Flow & Metababolism, 30, 46-50.