knnmi.all: Parallel Mutual Information Estimation Between All Matrix Rows
Description
A function that computes the mutual information between all pairs
of rows of matrix mat using entropy estimates from K-nearest neighbor distances.
Usage
knnmi.all(mat, k=3, noise=1e-12)
Arguments
mat
a numeric matrix (for the reconstruction of gene regulatory
networks, genes on rows and samples on columns).
k
the number of nearest neighbors to consider to estimate the
mutual information. Must be less than the number of columns of mat.
noise
the magnitude of the random noise added to break ties.
Details
The function adds a small random noise to the data in order to break ties due
to limited numerical precision.
By default, the function uses all the available cores. You can
set the actual number of threads used to N by exporting the
environment variable OMP_NUM_THREADS=N.
References
Kraskov, Alexander and Stogbauer, Harald and Grassberger, Peter.
Estimating mutual information. Phys. Rev. E, 2004.