quadfactor

Internal utility to calculate a constant quadratic factor for
 gene-level statistics
 variances over all pedigrees, for either autosomes or X chromosome

Gene-level variant association tests with disease status for pedigree data: kernel and burden association statistics.

Jason Sinnwell

pedgene

Gene-Level Variant Association Tests for Pedigree Data

Schaid Daniel

Visconti Alessia

quadfactor function

<dl> <dt>kinmat</dt>
<dd>A kinship matrix for one or more pedigrees</dd> <dt>chrom</dt>
<dd>character string for chromosome number, if "X", the
 method accounts for sex code</dd> <dt>resid</dt>
<dd>the residual based on the trait minus the group mean or
 adjusted trait value for each subject</dd> <dt>sex</dt>
<dd>See pedgene</dd> <dt>male.dose</dt>
<dd>See pedgene</dd></dl>

Arguments

Daniel J. Schaid, Mayo Clinic (schaid@mayo.edu).

Author

Internal utility to calculate a constant quadratic factor for
  gene-level statistics variances, over all pedigrees — quadfactor

<dl>

 <dt>kinmat</dt>
<dd>A kinship matrix for one or more pedigrees</dd>

 <dt>chrom</dt>
<dd>character string for chromosome number, if "X", the
 method accounts for sex code</dd>

 <dt>resid</dt>
<dd>the residual based on the trait minus the group mean or
 adjusted trait value for each subject</dd>

 <dt>sex</dt>
<dd>See pedgene</dd>

 <dt>male.dose</dt>
<dd>See pedgene</dd>

</dl>

quadfactor: Internal utility to calculate a constant quadratic factor for gene-level statistics variances, over all pedigrees

Description

Usage

Value

Arguments

Author

See Also