baseline_data_default

This dataset contains age-specific cancer penetrance rates for both females and males.
As an example, the data is derived from the SEER program for colorectal cancer females and males.

datasets

Implements statistical methods for estimating disease penetrance in
family-based studies. Penetrance refers to the probability of disease§
manifestation in individuals carrying specific genetic variants. The package
provides tools for age-specific penetrance estimation, handling missing data,
and accounting for ascertainment bias in family studies.
Cite as: Kubista, N., Braun, D. & Parmigiani, G. (2024) <doi:10.48550/arXiv.2411.18816>.

Nicolas Kubista

penetrance

Methods for Penetrance Estimation in Family-Based Studies

BayesMendel Lab

baseline_data_default function

A data frame with 94 rows and 3 variables:<dl>
<dt>Age</dt>
<dd>Age in years</dd><dt>Female</dt>
<dd>Female baseline risk</dd><dt>Male</dt>
<dd>Male baseline risk</dd>
</dl>A data frame with 94 rows and 3 variables:<dl>
<dt>Age</dt>
<dd>Age in years (1 to 94)</dd><dt>Female</dt>
<dd>Penetrance rate for females</dd><dt>Male</dt>
<dd>Penetrance rate for males</dd>
</dl>

Format

Default Baseline Data — baseline_data_default

A data frame with 94 rows and 3 variables:<dl>
<dt>Age</dt>
<dd>Age in years</dd>

<dt>Female</dt>
<dd>Female baseline risk</dd>

<dt>Male</dt>
<dd>Male baseline risk</dd>


</dl>

A data frame with 94 rows and 3 variables:<dl>
<dt>Age</dt>
<dd>Age in years (1 to 94)</dd>

<dt>Female</dt>
<dd>Penetrance rate for females</dd>

<dt>Male</dt>
<dd>Penetrance rate for males</dd>


</dl>

baseline_data_default: Default Baseline Data

Description

Usage

Arguments

Format