pharmr (version 1.4.0)

evaluate_epsilon_gradient: evaluate_epsilon_gradient

Description

Evaluate the numeric epsilon gradient

The gradient is evaluated at the current model parameter values or optionally at the given parameter values. The gradient is done for each data record in the model dataset or optionally using the dataset argument. The gradient is done at the current eta values or optionally at the given eta values.

This function currently only support models without ODE systems

Usage

evaluate_epsilon_gradient(
  model,
  etas = NULL,
  parameters = NULL,
  dataset = NULL
)

Value

(data.frame) Gradient

Arguments

model

(Model) Pharmpy model

etas

(data.frame (optional)) Optional list of eta values

parameters

(list(str=numeric) (optional)) Optional list of parameters and values

dataset

(data.frame (optional)) Optional dataset

See Also

evaluate_eta_gradient : Evaluate the eta gradient

Examples

if (FALSE) {
model <- load_example_model("pheno_linear")
results <- load_example_modelfit_results("pheno_linear")
etas <- results$individual_estimates
evaluate_epsilon_gradient(model, etas=etas)
}