pharmr (version 1.4.0)

set_initial_estimates: set_initial_estimates

Description

Update initial parameter estimate for a model

Updates initial estimates of population parameters for a model. If the new initial estimates are out of bounds or NaN this function will raise.

Usage

set_initial_estimates(
  model,
  inits,
  move_est_close_to_bounds = FALSE,
  strict = TRUE
)

Value

(Model) Pharmpy model object

Arguments

model

(Model) Pharmpy model to update initial estimates

inits

(list(str=numeric)) Initial parameter estimates to update

move_est_close_to_bounds

(logical) Move estimates that are close to bounds. If correlation >0.99 the correlation will be set to 0.9, if variance is <0.001 the variance will be set to 0.01.

strict

(logical) Whether all parameters in input need to exist in the model. Default is TRUE

See Also

fix_parameters_to : Fixing and setting parameter initial estimates in the same function

unfix_paramaters_to : Unfixing parameters and setting a new initial estimate in the same

Examples

if (FALSE) {
model <- load_example_model("pheno")
results <- load_example_modelfit_results("pheno")
model$parameters$inits
model <- set_initial_estimates(model, results$parameter_estimates)
model$parameters$inits
model <- load_example_model("pheno")
model <- set_initial_estimates(model, list('POP_CL'=2.0))
model$parameters['POP_CL']
}