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pla (version 0.2)

Parallel Line Assays

Description

Parallel Line Assays: Completely randomized design, Randomized Block design, and Latin squares design. Balanced data are fitted as described in the Ph.Eur. In the presence of missing values complete data analysis can be performed (with computation of Fieller's confidence intervals for the estimated potency), or imputation of values can be applied. The package contains a script such that a pdf-document with a report of an analysis of an assay can be produced from an input file with data of the assay. Here no knowledge of R is needed by the user.

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Version

Install

install.packages('pla')

Monthly Downloads

26

Version

0.2

License

GPL (>= 2)

Maintainer

Last Published

September 9th, 2015

Functions in pla (0.2)

Diphteria

Diphteria vaccine - Intradermal challenge
Erythropoietin

Erythropoietin rDNA - Normocythaemic assay in mice
HepatitisB

An in-vitro assay of three hepatitis B vaccines against a standard
IPV

Inactivated poliomyelitis vaccine - Type 3
HeparinSodium

Heparin Sodium - European Pharmacopoeia (1997), 2.7.5
Vancomycin

Antibiotic agar diffusion assay on 6 plates
plotSamples

Scatter plot for parallel line models
assayModel-class

Create a parallel line assay model
HumanHepatitis

Human Hepatitis A immunoglobulin - Elisa
potency

Return or compute potency
HepatitisBvaccine

Hepatitis B vaccine
AgarDiffusionAssay

Antibiotic agar diffusion assay using a rectangular tray
Fiellers

Fiellers confidence interval
pla.plots

Make plots for parallel line models
FactorIX

Factor IX - Coagulation
assayTable2frame

reduceDimension

Reduce the number of dimensions by one
jitterSteps

Compute a perturbed version of the dose-variable
data2assayFrame

pheur325

Potency with confidence intervals
pla-package

Parallel Line Assays
readAssayTable

Read a .txt file with responses of an assay
Corticotrophin

An assay of corticotrophin by subcutaneous injection in rats
pla.fit

Estimation in parallel line models, with listing of results
Nystatin

Nystatin: Antibiotic agar diffusion assay
Erythromycin

Erythromycin - Assay 1
Turbidimetric

Antibiotic turbidimetric assay