saro.motif

Searches for S-aromatic motifs in proteins.

Contains utilities for the analysis of post-translational modifications (PTMs) in proteins,
with particular emphasis on the sulfoxidation of methionine residues. Features include the ability to download,
filter and analyze data from the sulfoxidation database 'MetOSite'. Utilities to search and characterize S-aromatic motifs in proteins are also provided.
In addition, functions to analyze sequence environments around modifiable residues in proteins can be found.
For instance, 'ptm' allows to search for amino acids either overrepresented or avoided around the modifiable
residues from the proteins of interest. Functions tailored to test statistical hypothesis related to
these differential sequence environments are also implemented.
Further and detailed information regarding the methods in this package can be found in (Aledo (2020) <https://metositeptm.com>).

Juan Aledo

Analyses of Protein Post-Translational Modifications

Juan Carlos Aledo

saro.motif function

<dl><dt>pdb</dt>
<dd>either the path to the PDB file of interest or the 4-letters identifier.</dd>
<dt>threshold</dt>
<dd>distance in ångströms, between the S atom and the aromatic ring centroid, used as threshold.</dd>
<dt>onlySaro</dt>
<dd>logical, if FALSE the output includes information about Met residues that are not involved in S-aromatic motifs.</dd></dl>

Arguments

Author

Search for S-Aromatic Motifs — saro.motif

<dl>

<dt>pdb</dt>
<dd>either the path to the PDB file of interest or the 4-letters identifier.</dd>


<dt>threshold</dt>
<dd>distance in ångströms, between the S atom and the aromatic ring centroid, used as threshold.</dd>


<dt>onlySaro</dt>
<dd>logical, if FALSE the output includes information about Met residues that are not involved in S-aromatic motifs.</dd>

</dl>

saro.motif: Search for S-Aromatic Motifs

Description

Usage

Value

Arguments

Author

Details

References

See Also

Examples