gsimC

This function simulates phenotype data by random sampling of markers available on `Glist`.
Default parameters for the simulated phenotype reflect the genetic architecture assumed by BayesC prior(Habier et al., 2011).
This function is under active development.

internal

Provides an infrastructure for efficient processing of large-scale genetic and phenotypic data including core functions for: 1) fitting linear mixed models, 2) constructing marker-based genomic relationship matrices, 3) estimating genetic parameters (heritability and correlation), 4) performing genomic prediction and genetic risk profiling, and 5) single or multi-marker association analyses.
Rohde et al. (2019) <doi:10.1101/503631>.

Peter Soerensen

Statistical Tools for Quantitative Genetic Analyses

Palle Duun Rohde

Izel Fourie Soerensen

gsimC function

<dl><dt>Glist</dt>
<dd>A list containing genetic data. If NULL, the function will stop with an error.</dd>
<dt>h2</dt>
<dd>Heritability. If NULL, heritability of 0.5 is assumed.</dd>
<dt>m</dt>
<dd>Number of causal markers. The values for either `m` or `prp.cau` should be provided at any given time. 
If the list of quality controlled markers is not available then list of raw markers is used. 
If `m` is NULL and `prp.cau` is also NULL, `prp.cau` will default to 0.001.</dd>
<dt>prp.cau</dt>
<dd>Proportion of causal markers. The values for either `m` or `prp.cau` should be provided at any given time.</dd>
<dt>n</dt>
<dd>Number of individuals randomly sampled from `Glist`. If NULL, all the individuals on `Glist` is used.</dd></dl>

Arguments

Peter Soerensen
Merina Shrestha

Author

Simulate Genetic Data Based on Given Parameters — gsimC

<dl>

<dt>Glist</dt>
<dd>A list containing genetic data. If NULL, the function will stop with an error.</dd>


<dt>h2</dt>
<dd>Heritability. If NULL, heritability of 0.5 is assumed.</dd>


<dt>m</dt>
<dd>Number of causal markers. The values for either `m` or `prp.cau` should be provided at any given time. 
If the list of quality controlled markers is not available then list of raw markers is used. 
If `m` is NULL and `prp.cau` is also NULL, `prp.cau` will default to 0.001.</dd>


<dt>prp.cau</dt>
<dd>Proportion of causal markers. The values for either `m` or `prp.cau` should be provided at any given time.</dd>


<dt>n</dt>
<dd>Number of individuals randomly sampled from `Glist`. If NULL, all the individuals on `Glist` is used.</dd>

</dl>

gsimC: Simulate Genetic Data Based on Given Parameters

Description

Usage

Value

Arguments

Author