predict_auc_mt_cc

Computes the expected Area Under the Curve (AUC) for predicting a binary trait using 
information on a correlated binary trait.

internal

Provides an infrastructure for efficient processing of large-scale genetic and phenotypic data including core functions for: 1) fitting linear mixed models, 2) constructing marker-based genomic relationship matrices, 3) estimating genetic parameters (heritability and correlation), 4) performing genomic prediction and genetic risk profiling, and 5) single or multi-marker association analyses.
Rohde et al. (2019) <doi:10.1101/503631>.

Peter Soerensen

Statistical Tools for Quantitative Genetic Analyses

Palle Duun Rohde

Izel Fourie Soerensen

predict_auc_mt_cc function

<dl><dt>h2x</dt>
<dd>Heritability of the target trait.</dd>
<dt>Nx</dt>
<dd>Number of samples for the target trait.</dd>
<dt>Kx</dt>
<dd>Prevalence of the target trait.</dd>
<dt>Px</dt>
<dd>Case-control proportion of the target trait.</dd>
<dt>h2y</dt>
<dd>Heritability of the correlated trait.</dd>
<dt>Ny</dt>
<dd>Number of samples for the correlated trait.</dd>
<dt>Ky</dt>
<dd>Prevalence of the correlated trait.</dd>
<dt>Py</dt>
<dd>Case-control proportion of the correlated trait.</dd>
<dt>rg</dt>
<dd>Genetic correlation between the target and the correlated trait.</dd>
<dt>Me</dt>
<dd>Number of independent chromosome segments.</dd>
<dt>M</dt>
<dd>Number of markers.</dd></dl>

Arguments

Expected AUC for prediction of a binary trait using information on correlated binary trait — predict_auc_mt_cc

<dl>

<dt>h2x</dt>
<dd>Heritability of the target trait.</dd>


<dt>Nx</dt>
<dd>Number of samples for the target trait.</dd>


<dt>Kx</dt>
<dd>Prevalence of the target trait.</dd>


<dt>Px</dt>
<dd>Case-control proportion of the target trait.</dd>


<dt>h2y</dt>
<dd>Heritability of the correlated trait.</dd>


<dt>Ny</dt>
<dd>Number of samples for the correlated trait.</dd>


<dt>Ky</dt>
<dd>Prevalence of the correlated trait.</dd>


<dt>Py</dt>
<dd>Case-control proportion of the correlated trait.</dd>


<dt>rg</dt>
<dd>Genetic correlation between the target and the correlated trait.</dd>


<dt>Me</dt>
<dd>Number of independent chromosome segments.</dd>


<dt>M</dt>
<dd>Number of markers.</dd>

</dl>

predict_auc_mt_cc: Expected AUC for prediction of a binary trait using information on correlated binary trait

Description

Usage

Value

Arguments