Learn R Programming

qtl (version 1.70)

max.scanPhyloQTL: Maximum peak in genome scan to map a QTL to a phylogenetic tree

Description

Print the chromosome with the maximum LOD score across partitions, from the results of scanPhyloQTL.

Usage

# S3 method for scanPhyloQTL
max(object, chr, format=c("postprob", "lod"),
        ...)

Value

An object of class summary.scanPhyloQTL, to be printed by

print.summary.scanPhyloQTL.

Arguments

object

An object output by the function scanPhyloQTL.

chr

Optional vector indicating the chromosomes to consider. This should be a vector of character strings referring to chromosomes by name; numeric values are converted to strings. Refer to chromosomes with a preceding - to have all chromosomes but those considered. A logical (TRUE/FALSE) vector may also be used.

format

Indicates whether to provide LOD scores or approximate posterior probabilities; see the help file for summary.scanPhyloQTL.

...

Ignored at this point.

Author

Karl W Broman, broman@wisc.edu

Details

The output, and the use of the argument format, is as in summary.scanPhyloQTL.

References

Broman, K. W., Kim, S., An\'e, C. and Payseur, B. A. Mapping quantitative trait loci to a phylogenetic tree. In preparation.

See Also

scanPhyloQTL, plot.scanPhyloQTL, summary.scanPhyloQTL, max.scanone, inferredpartitions, simPhyloQTL

Examples

Run this code
if (FALSE) {
# example map; drop X chromosome
data(map10)
map10 <- map10[1:19]

# simulate data
x <- simPhyloQTL(4, partition="AB|CD", crosses=c("AB", "AC", "AD"),
                 map=map10, n.ind=150,
                 model=c(1, 50, 0.5, 0))

# run calc.genoprob on each cross
x <- lapply(x, calc.genoprob, step=2)

# scan genome, at each position trying all possible partitions
out <- scanPhyloQTL(x, method="hk")

# maximum peak
max(out, format="lod")

# approximate posterior probabilities at peak
max(out, format="postprob")

# all peaks above a threshold for LOD(best) - LOD(2nd best)
summary(out, threshold=1, format="lod")

# all peaks above a threshold for LOD(best), showing approx post'r prob
summary(out, format="postprob", threshold=3)

# plot of results
plot(out)
}

Run the code above in your browser using DataLab