For d!=0 it calculates the ratio of information in the
middle of a marker interval of length d cM to the cost of
genotyping the cross. For d=0, it calculates the ratio of
information at any locus to the cost of genotyping the cross.
Arguments
sel.frac
Selection fraction; proportion of individuals genotyped
cost
Genotyping cost in units of raising an individual. When
d=0 (dense genotyping), it is the cost of genotyping an
individual. When d!=0, it is the cost of a single marker
genotype in an individual.
d
Marker spacing in centiMorgans
G
Genome size in Morgans
cross
Cross type, "bc"or "f2"
Author
Saunak Sen, Jaya Satagopan, Karl Broman, and Gary Churchill
Details
The information calculations are done under the null hypothesis
of no QTL effect.
References
Sen S, Satagopan JM, Churchill GA (2005)
Quantitative trait locus study design from an information perspective.
Genetics, 170:447-64.