In the first form, with the selection fraction specified, the
spacing in centiMorgans that maximizes the information to cost ratio
in the middle of the marker interval. In the second form, with the
selection fraction unspecified, it returns the value of
(spacing,sel.frac) which maximizes the information
to cost ratio in the middle of the marker interval.
Arguments
cost
Cost of genotyping in units of raising an individual
sel.frac
Selection fraction; proportion of individuals genotyped
G
Genome size in centiMorgans
cross
Cross type, "bc" or "f2"
Author
Saunak Sen, Jaya Satagopan, Karl Broman, and Gary Churchill
Details
The function optim is used to search for the optima.
References
Sen S, Satagopan JM, Churchill GA (2005)
Quantitative trait locus study design from an information perspective.
Genetics, 170:447-64.