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repfdr

Replicability Analysis for Multiple Studies of High Dimension. Estimates Bayes and local Bayes false discovery rates for replicability analysis.

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Install

install.packages('repfdr')

Monthly Downloads

432

Version

1.1-3

License

GPL (>= 2)

Issues

0

Pull Requests

0

Stars

2

Forks

3

Maintainer

Ruth Heller

Last Published

April 6th, 2015

Functions in repfdr (1.1-3)

hconfigs

Enumeration of all possible vectors of association status.
em.control

Control Parameters for the EM algorithm
binned_zmat_sim

Simulated data set - input objects to main function
ztobins

Binning of z-scores and estimation of the probabilities in each bin for the null and non-null states.
repfdr

Bayes and local Bayes false discovery rate estimation for replicability analysis
SNPlocations

Three GWAS studies SNPs locations and data
piem

Estimation of the prior probabilities for each association status vector.
zmat_sim

Simulated data set
binned_zmat

Three GWAS studies - input objects to main function
hmat_sim

Simulated data set - indicators of association status matrix
ldr

Estimation of posterior probabilities for the vectors of association status