# NOT RUN {
warperNoStrata <- function(n, ...){
newdata <- data.frame(X1=0,X6=0)
time <- 1
m <- lvm()
regression(m) <- y ~ X6 + X1
distribution(m,~X1) <- binomial.lvm()
distribution(m,~cens) <- coxWeibull.lvm(scale=1)
distribution(m,~y) <- a <- coxWeibull.lvm(scale=0.3)
eventTime(m) <- eventtime ~ min(y=1,cens=0)
d <- as.data.table(sim(m,n))
setkey(d, eventtime)
m.cox <- coxph(Surv(eventtime, status) ~ X1+X6,
data = d, y = TRUE, x = TRUE)
survNoStrata <- predictCox(m.cox, type = "survival",
newdata = newdata, times = time, iid = TRUE, se = TRUE)
mStrata.cox <- coxph(Surv(eventtime, status) ~ strata(X1)+X6,
data = d, y = TRUE, x = TRUE)
survStrata <- predictCox(mStrata.cox, type = "survival",
newdata = newdata, times = time, iid = TRUE, se = TRUE)
res <- influenceTest(survStrata, survNoStrata, type = "survival")
return(res)
}
warperStrata <- function(n, ...){
newdata <- data.frame(X1=0,X6=0)
time <- 1
m <- lvm()
regression(m) <- y ~ X6
regression(m) <- s ~ exp(-2*X1)
distribution(m,~X1) <- binomial.lvm()
distribution(m,~cens) <- coxWeibull.lvm(scale=1)
distribution(m,~y) <- a <- coxWeibull.lvm(scale=0.3,shape=~s)
eventTime(m) <- eventtime ~ min(y=1,cens=0)
d <- as.data.table(sim(m,n))
setkey(d, eventtime)
m.cox <- coxph(Surv(eventtime, status) ~ X1+X6, data = d, y = TRUE, x = TRUE)
survNoStrata <- predictCox(m.cox, type = "survival",
newdata = newdata, times = time, iid = TRUE, se = TRUE)
mStrata.cox <- coxph(Surv(eventtime, status) ~ strata(X1)+X6, data = d, y = TRUE, x = TRUE)
survStrata <- predictCox(mStrata.cox, type = "survival",
newdata = newdata, times = time, iid = TRUE, se = TRUE)
res <- influenceTest(survStrata, survNoStrata, type = "survival")
return(res)
}
n <- 500
resNoStrata <- pbsapply(1:200, warperNoStrata, n = n)
sd(unlist(resNoStrata["delta",]))
quantile(unlist(resNoStrata["se.delta",]))
mean(unlist(resNoStrata["p.value",])<0.05)
resStrata <- pbsapply(1:100, warperStrata, n = n)
sd(unlist(resStrata["delta",]))
quantile(unlist(resStrata["se.delta",]))
mean(unlist(resStrata["p.value",])<0.05)
# }
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