if (FALSE) {
## try after you get the repeated package
library(repeated)
times <- rep(1:20,2)
dose <- c(rep(2,20),rep(5,20))
mu <- function(p) exp(p[1]-p[3])*(dose/(exp(p[1])-exp(p[2]))*
(exp(-exp(p[2])*times)-exp(-exp(p[1])*times)))
shape <- function(p) exp(p[1]-p[2])*times*dose*exp(-exp(p[1])*times)
conc <- matrix(rgamma(40,1,scale=mu(log(c(1,0.3,0.2)))),ncol=20,byrow=TRUE)
conc[,2:20] <- conc[,2:20]+0.5*(conc[,1:19]-matrix(mu(log(c(1,0.3,0.2))),
ncol=20,byrow=TRUE)[,1:19])
conc <- ifelse(conc>0,conc,0.01)
z <- gar(conc, dist="gamma", times=1:20, mu=mu, shape=shape,
preg=log(c(1,0.4,0.1)), pdepend=0.5, pshape=log(c(1,0.2)))
# plot individual profiles and the average profile
plot(iprofile(z), nind=1:2, pch=c(1,20), lty=3:4)
plot(mprofile(z), nind=1:2, lty=1:2, add=TRUE)
}
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