This function returns a list with elements mainly generated from sigclust2.
sigp(test_dat, minSize = 10, sim = 100)
A list with the following elements:
p
: p-value for the first split
z
: z-score for the first split
shc_result
: a shc
S3-object as defined in sigclust2 package
clust2
: a vector with group index for each cell
clust_dat
: a matrix of data representation used as input for hierarchical clustering
A UMI count data matrix with samples to cluster as rows and features as columns.
A numeric value specifying the minimal allowable cluster size (the number of cells for the smallest cluster, default 10).
A numeric value specifying the number of simulations during the Monte Carlo simulation procedure (default 100).
This is a function used to calculate the significance level of the first split from hierarchical clustering based on euclidean distance and Ward's linkage.
kimes2017statisticalscpoisson Rclusterppscpoisson