Finds borders between distinct regions constituting signal peptides using a heuristic algorithm.
find_nhc(protein, signal = NULL)
a vector of amino acids or object of class
SeqFastaAA
.
range of signal peptide. If NULL
, the attribute sig
of protein
will be used.
a vector of length 4 containing positions of:
start of n-region,
start of h-region,
start of c-region,
cleavage site.
Henrik Nielsen, Anders Krogh (1998). Prediction of signal peptides and signal anchors by a hidden Markov model. Proc. Sixth Int. Conf. on Intelligent Systems for Molecular Biology.