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sommer (version 3.2)

Solving Mixed Model Equations in R

Description

Structural multivariate-univariate linear mixed model solver for multiple random effects allowing the specification of variance-covariance structures for random effects and allowing the fit of heterogeneous variance models (Covarrubias-Pazaran, 2016 ; Maier et al., 2015 ). ML/REML estimates can be obtained using the Direct-Inversion Newton-Raphson, and Efficient Mixed Model Association algorithms. Designed for genomic prediction and genome wide association studies (GWAS), particularly focused in the p > n problem (more coefficients than observations) to include multiple relationship matrices or other covariance structures.

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Version

Install

install.packages('sommer')

Monthly Downloads

7,425

Version

3.2

License

GPL-3

Maintainer

Giovanny Covarrubias-Pazaran

Last Published

January 9th, 2018

Functions in sommer (3.2)

F1geno

Genotypes from an F1(CP) cross to show phasing
FDdata

Full diallel data for corn hybrids
EM

Expectation Maximization Algorithm
ExpDesigns

Data for different experimental designs
D.mat

Dominance relationship matrix
E.mat

Epistatic relationship matrix
adiag1

Binds arrays corner-to-corner
and

and functionality
blockerT

Applying transversal postblocking in a field
brewer.pal

Generate a sequence of colors for groups.
anova.MMERM

anova form a GLMM fitted with mmer
at

at functionality
eig

eigen decomposition functionality
example

Broad sense heritability calculation.
BTdata

Blue Tit Data for a Quantitative Genetic Experiment
CPdata

Genotypic and Phenotypic data for a CP population
GWAS

Genome Wide Association Analysis
fill.design

Filling the design of an experiment
fitted.MMERM

fitted form a GLMM fitted with mmer
imputev

Imputing a numeric or character vector
is.diagonal.matrix

Test for diagonal square matrix
A.mat

Additive relationship matrix
AI

Average Information Algorithm
matrix.trace

The trace of a matrix
maxi.qtl

Peak search by first derivatives
randef

extracting random effects
gryphondata

Gryphon data from the Journal of Animal Ecology
h2.fun

Obtain heritabilities with three different methods
manhattan

Creating a manhattan plot
MNR

Multivariate Newton-Raphson Algorithm
PolyData

Genotypic and Phenotypic data for a potato polyploid population
bathy.colors

Generate a sequence of colors for plotting bathymetric data.
big.peaks.col

Peak search by first derivatives
h2example

Broad sense heritability calculation.
residuals.MMERM

Residuals form a GLMM fitted with mmer
map.plot

Creating a genetic map plot
overlay

Overlay Matrix
pedtoK

Pedigree to matrix
vctable

vctable functionality
RICE

Rice lines dataset
Technow_data

Genotypic and Phenotypic data from single cross hybrids (Technow et al. (2014))
blocker

Applying postblocking in a field
blockerL

Applying linear postblocking in a field
cornHybrid

Corn crosses and markers
design.score

design score for the model to be tested
vctable.help

vctable.help functionality
g

g functionality
grp

grouping functionality
plot.MMERM

plot form a LMM plot with mmer
plot.variogram.MMERM

Default variogram.MMERM plotting
wheatLines

wheat lines dataset
HDdata

half diallel data for corn hybrids
MEMMA

Multivariate Efficient Mixed Model Association Algorithm
fdr

False Discovery Rate calculation
hadamard.prod

Hadamard product of two matrices
my.colors

All typical colors in R easy to access.
nna

Nearest neighbour adjustment
phase.F1

Phasing F1 (CP) data in biparental populations
pin

pin functionality
us

us functionality
variogram

Sample variogram
yates.oats

Yield of oats in a split-block experiment
hdm

Half Diallel Matrix
hits

Creating a fixed effect matrix with significant GWAS markers
mmer

mixed model equations in R
mmer2

mixed model equations in R
summary.MMERM

summary form a GLMM fitted with mmer
transp

Creating color with transparency
fdr2

False Discovery Rate calculation
GWAS2

Genome Wide Association Analysis
atcg1234

Letter to number converter
augment

augment design example.
build.HMM

Build a hybrid marker matrix using parental genotypes
coef.MMERM

coef form a GLMM fitted with mmer
is.square.matrix

Test for square matrix
jet.colors

Generate a sequence of colors alog the jet colormap.
score.calcMV

Score calculation for markers
sommer-package

Solving Mixed Model Equations in R Figure: mai.png