calculateDropout calculate drop-out events (allele
and locus) and records the surviving peak height.
Usage
calculateDropout(data, ref, ignoreCase = TRUE)
Arguments
data
data frame in GeneMapper format containing at
least a column 'Allele'.
ref
data frame in GeneMapper format.
ignoreCase
logical, default TRUE for case
insensitive.
Value
data.frame with columns 'Dropout', indicating no dropout
(0), allele (1) and locus dropout (2), and 'Rfu',
'Heterozygous'.
Details
Calculates drop-out events. In case of allele dropout the
peak height of the surviving allele is given. NB! "Sample
Names" in 'ref' must be unique 'core' name of replicate
sample names in 'data'. NB! Homozygous alleles must be
doubled (X -> X/X).