tipr (version 1.0.2)

adjust_hr: Adjust an observed hazard ratio for a normally distributed confounder

Description

Adjust an observed hazard ratio for a normally distributed confounder

Usage

adjust_hr(
  effect_observed,
  exposure_confounder_effect,
  confounder_outcome_effect,
  verbose = getOption("tipr.verbose", TRUE),
  hr_correction = FALSE
)
adjust_hr_with_continuous(
  effect_observed,
  exposure_confounder_effect,
  confounder_outcome_effect,
  verbose = getOption("tipr.verbose", TRUE),
  hr_correction = FALSE
)

Value

Data frame.

Arguments

effect_observed

Numeric positive value. Observed exposure - outcome hazard ratio. This can be the point estimate, lower confidence bound, or upper confidence bound.

exposure_confounder_effect

Numeric. Estimated difference in scaled means between the unmeasured confounder in the exposed population and unexposed population

confounder_outcome_effect

Numeric. Estimated relationship between the unmeasured confounder and the outcome.

verbose

Logical. Indicates whether to print informative message. Default: TRUE

hr_correction

Logical. Indicates whether to use a correction factor. The methods used for this function are based on risk ratios. For rare outcomes, a hazard ratio approximates a risk ratio. For common outcomes, a correction factor is needed. If you have a common outcome (>15%), set this to TRUE. Default: FALSE.

Examples

adjust_hr(0.9, -0.9, 1.3)