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trioGxE (version 0.1-1)

A data smoothing approach to explore and test gene-environment interaction in case-parent trio data

Description

The package contains functions that 1) estimates gene-environment interaction between a SNP and a continuous non-genetic attribute by fitting a generalized additive model to case-parent trio data, 2) produces graphical displays of estimated interaction, 3) performs permutation test of gene-environment interaction; 4) simulates informative case-parent trios.

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Version

Install

install.packages('trioGxE')

Monthly Downloads

15

Version

0.1-1

License

GPL-2

Maintainer

Last Published

April 2nd, 2013

Functions in trioGxE (0.1-1)

hypoTrioDat

Simulated data for a hypothetical example
test.trioGxE

Test of gene-environment interaction between a SNP and a continuous non-genetic covariate from case-parent trio data.
trioSim

Simulate informative case-parent trios
trioGxE

Generalized additive model estimation of gene-environment interaction using data from case-parent trios
plot.trioGxE

Graphical display of gene-environment interaction between a SNP and a continuous non-genetic attribute in case-parent trio data
pirls.trio-internal

Internal pirls.trio Functions