generate_parameter

Internal function used to generate parameters based on IIV information

internal

Complete work flow for the analysis of pharmacokinetic pharmacodynamic (PKPD), physiologically-based pharmacokinetic (PBPK) and systems pharmacology models including: creation of ordinary differential equation-based models, pooled parameter estimation, individual/population based simulations, rule-based simulations for clinical trial design and modeling assays, deployment with a customizable 'Shiny' app, and non-compartmental analysis. System-specific analysis templates can be generated and each element includes integrated reporting with 'PowerPoint' and 'Word'.

John Harrold

ubiquity

PKPD, PBPK, and Systems Pharmacology Modeling Tools

generate_parameter function

<dl><dt>SIMINT_parameters</dt>
<dd>parameters vector containing the typical values</dd>
<dt>SIMINT_cfg</dt>
<dd>ubiquity system object</dd>
<dt>SIMINT_PARAMETER_TV</dt>
<dd>Typical value of the parameter in question</dd>
<dt>SIMINT_IIV_VALUE</dt>
<dd>sample from mvr distribution</dd>
<dt>SIMINT_equation</dt>
<dd>equation relating IIV and typical value to the parameter value with variability</dd></dl>

Arguments

Generates a Parameter Based on &lt;IIV:?&gt; in the System File — generate_parameter

<dl>

<dt>SIMINT_parameters</dt>
<dd>parameters vector containing the typical values</dd>


<dt>SIMINT_cfg</dt>
<dd>ubiquity system object</dd>


<dt>SIMINT_PARAMETER_TV</dt>
<dd>Typical value of the parameter in question</dd>


<dt>SIMINT_IIV_VALUE</dt>
<dd>sample from mvr distribution</dd>


<dt>SIMINT_equation</dt>
<dd>equation relating IIV and typical value to the parameter value with variability</dd>

</dl>

generate_parameter: Generates a Parameter Based on `<IIV:?>` in the System File

Description

Usage

Value

Arguments