make_forcing_function

Takes a list of times, values, and an interpolation method

internal

Complete work flow for the analysis of pharmacokinetic pharmacodynamic (PKPD), physiologically-based pharmacokinetic (PBPK) and systems pharmacology models including: creation of ordinary differential equation-based models, pooled parameter estimation, individual/population based simulations, rule-based simulations for clinical trial design and modeling assays, deployment with a customizable 'Shiny' app, and non-compartmental analysis. System-specific analysis templates can be generated and each element includes integrated reporting with 'PowerPoint' and 'Word'.

John Harrold

ubiquity

PKPD, PBPK, and Systems Pharmacology Modeling Tools

make_forcing_function function

<dl><dt>times</dt>
<dd>time values for the forcing function</dd>
<dt>values</dt>
<dd>magnitude for each time (same length of time)</dd>
<dt>type</dt>
<dd>string indicating the type of forcing function can be one of the following:<ul>
<li><code>"step"</code> for constant values that switch to new values at the times</li>
<li><code>"linear"</code> to linearly interpolate between the points</li>
</ul></dd>
<dt>output_times</dt>
<dd>vector of simulation output times</dd>
<dt>sample_delta_mult</dt>
<dd>multiplier used to control the magnitude of spacing around event times</dd></dl>

Arguments

Makes Forcing Function From Times and Values — make_forcing_function

<dl>

<dt>times</dt>
<dd>time values for the forcing function</dd>


<dt>values</dt>
<dd>magnitude for each time (same length of time)</dd>


<dt>type</dt>
<dd>string indicating the type of forcing function can be one of the following:<ul>
<li><code>"step"</code> for constant values that switch to new values at the times</li>
<li><code>"linear"</code> to linearly interpolate between the points</li>
</ul></dd>


<dt>output_times</dt>
<dd>vector of simulation output times</dd>


<dt>sample_delta_mult</dt>
<dd>multiplier used to control the magnitude of spacing around event times</dd>

</dl>

make_forcing_function: Makes Forcing Function From Times and Values

Description

Usage

Value

Arguments