sample_around

When events, such as bolus doses, are applied to the system
rapid changes can occur. If the system is not sampled heavily around these
times, these changes may be missed in the output profiles. Based on the total
duration of the sample times, extra samples can be added near these events.

internal

Complete work flow for the analysis of pharmacokinetic pharmacodynamic (PKPD), physiologically-based pharmacokinetic (PBPK) and systems pharmacology models including: creation of ordinary differential equation-based models, pooled parameter estimation, individual/population based simulations, rule-based simulations for clinical trial design and modeling assays, deployment with a customizable 'Shiny' app, and non-compartmental analysis. System-specific analysis templates can be generated and each element includes integrated reporting with 'PowerPoint' and 'Word'.

John Harrold

ubiquity

PKPD, PBPK, and Systems Pharmacology Modeling Tools

sample_around function

<dl><dt>tvals</dt>
<dd>vector of event times</dd>
<dt>ot</dt>
<dd>simualtion output times</dd>
<dt>sample_delta_mult</dt>
<dd>multiplier used to control the magnitude of spacing around and following event times</dd></dl>

Arguments

Define Sample Times Around Events — sample_around

<dl>

<dt>tvals</dt>
<dd>vector of event times</dd>


<dt>ot</dt>
<dd>simualtion output times</dd>


<dt>sample_delta_mult</dt>
<dd>multiplier used to control the magnitude of spacing around and following event times</dd>

</dl>

sample_around: Define Sample Times Around Events

Description

Usage

Value

Arguments

Details