system_set_guess

Default values for parameters are taken from the <code>system.txt</code> file
either when the parameter was defined (<code>&lt;P&gt;</code>) or when it was reassigned
for a parameter set (<code>&lt;PSET:?:?&gt;?</code>). These can be altered at the
scripting level using this function.

Complete work flow for the analysis of pharmacokinetic pharmacodynamic (PKPD), physiologically-based pharmacokinetic (PBPK) and systems pharmacology models including: creation of ordinary differential equation-based models, pooled parameter estimation, individual/population based simulations, rule-based simulations for clinical trial design and modeling assays, deployment with a customizable 'Shiny' app, and non-compartmental analysis. System-specific analysis templates can be generated and each element includes integrated reporting with 'PowerPoint' and 'Word'.

John Harrold

ubiquity

PKPD, PBPK, and Systems Pharmacology Modeling Tools

system_set_guess function

<dl><dt>cfg</dt>
<dd>ubiquity system object</dd>
<dt>pname</dt>
<dd>name of parameter to set</dd>
<dt>value</dt>
<dd>value to assign</dd>
<dt>lb</dt>
<dd>optionally change the lower bound (<code>NULL</code>)</dd>
<dt>ub</dt>
<dd>optionally change the upper bound (<code>NULL</code>)</dd></dl>

Arguments

Alter Initial Guess and Parameter Bounds — system_set_guess

<dl>

<dt>cfg</dt>
<dd>ubiquity system object</dd>


<dt>pname</dt>
<dd>name of parameter to set</dd>


<dt>value</dt>
<dd>value to assign</dd>


<dt>lb</dt>
<dd>optionally change the lower bound (<code>NULL</code>)</dd>


<dt>ub</dt>
<dd>optionally change the upper bound (<code>NULL</code>)</dd>

</dl>

system_set_guess: Alter Initial Guess and Parameter Bounds

Description

Usage

Value

Arguments

Details