compute_all_post_prob

ploidy

A matrix of variational posterior means. The rows
index the individuals and the columns index the SNPs.

A matrix of variational posterior variances.
The rows index the individuals and the columns index the SNPs.

sigma2

A vector of allele frequencies for all SNPs.

alpha

A vector of inbreeding coefficients for all individuals.

Computes every posterior probability for each dosage level for
each individual at each SNP.

internal

Implements empirical Bayes approaches to genotype
polyploids from next generation sequencing data while
accounting for allelic bias, overdispersion, and sequencing
error. The main function is flexdog(), which allows the specification
of many different genotype distributions. An experimental
function that takes into account varying levels of relatedness
is implemented in mupdog(). Also provided are functions to
simulate genotypes, rgeno(), and read-counts, rflexdog(), as well as
functions to calculate oracle genotyping error rates, oracle_mis(), and
correlation with the true genotypes, oracle_cor(). These latter two
functions are useful for read depth calculations. Run
browseVignettes(package = "updog") in R for example usage. See
Gerard et al. (2018) <doi:10.1534/genetics.118.301468> and
Gerard and Ferrao (2019) <doi:10.1093/bioinformatics/btz852> for details
on the implemented methods.

compute_all_post_prob: Computes every posterior probability for each dosage level for each individual at each SNP.

Description

Usage

Arguments

Value