viper (version 1.6.0)

integrateSignatures: Integrate signatures

Description

This function integrates signatures represented as columns in the input matrix using self-weighting average

Usage

integrateSignatures(signature, score = 1)

Arguments

signature

Numeric matrix containing the signatures as z-scores or NES, genes in rows and signatures in columns

score

Number indicating the exponent score for the weight

Value

Vector containing the integrated signatures

Examples

data(bcellViper, package="bcellViper")
sig <- bootstrapTtest(dset, "description", "CB", "N", per=100)
isig <- integrateSignatures(sig)
plot(density(sig))
lines(density(isig, adj=1.5), col="red")